Long-Term Outcome of Second-Line Antiretroviral Therapy in Resource-Limited Settings
نویسندگان
چکیده
منابع مشابه
Improving first-line antiretroviral therapy in resource-limited settings.
PURPOSE OF REVIEW Access to first-line antiretroviral therapy in resource-limited settings has increased rapidly in the last 5 years. Newer medicines with greater potency and better safety profiles open the possibility for improving first-line antiretroviral therapy for developing countries. RECENT FINDINGS Several medicines offer the potential to improve the simplicity, safety and efficacy o...
متن کاملEmergence of HIV drug resistance during first- and second-line antiretroviral therapy in resource-limited settings.
INTRODUCTION Antiretroviral therapy (ART) in resource-limited settings has expanded in the last decade, reaching >8 million individuals and reducing AIDS mortality and morbidity. Continued success of ART programs will require understanding the emergence of HIV drug resistance patterns among individuals in whom treatment has failed and managing ART from both an individual and public health persp...
متن کاملLong-term adherence to antiretroviral therapy in resource-limited settings: a bitter pill to swallow.
Adherence to antiretroviral therapy is an important predictor of long-term treatment success. Adherence can be differentiated between early adherence challenges, that are about integrating pill-taking into daily life, and long-term adherence, where patients struggle to maintain clinical connections and interrupt clinical care and medication use. In resource-limited settings, treatment interrupt...
متن کاملSwitching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring.
BACKGROUND In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring is not generally available in resource-limited settings. We examined switching from nonnucleoside reverse transcriptase inhibitor (NNRTI)-based first-line regimens to protease inhibitor-based regimens in Africa, Sou...
متن کاملTreatment outcomes of patients on second-line antiretroviral therapy in resource-limited settings: a systematic review and meta-analysis.
BACKGROUND A growing proportion of patients on antiretroviral therapy in resource-limited settings have switched to second-line regimens. We carried out a systematic review in order to summarize reported rates and reasons for virological failure among people on second-line therapy in resource-limited settings. METHODS Two reviewers independently searched four databases and three conference we...
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ژورنال
عنوان ژورنال: Journal of the International Association of Providers of AIDS Care (JIAPAC)
سال: 2014
ISSN: 2325-9582,2325-9582
DOI: 10.1177/2325957414527167